Pilot study to identify biomarkers for tolerance to liver grafts
- Conditions
- liver graftsrejection10019654
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 77
Case control study: The experimental group consists of 8 LTx patients in
Erasmus MC that are currently at least 6 months free of IS. 5 additional
patients are currently in the process of IS reduction, and will be included as
soon as they are 6 months free of IS. As a control group we will include 39 LTx
patients matched with the experimental group for LTx-indication and time after
LTx and have been continuously treated with IS., Cohort study: LTx-recipients
in Erasmus MC in which for clinical reasons IS will be gradually withdrawn. Our
estimation is that we can include 25 patients during the next 4 years, but this
is fully dependent on clinical need to reduce and finally stop IS.
Severe recurrence of primary liver disease with development of cirrhosis.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method