Safety and efficacy of cervical administration of misoprostol in induction of labor compared to vaginal and sublingual administratio
Phase 3
Not yet recruiting
- Conditions
- abour induction.Failed induction of labour
- Registration Number
- IRCT20200421047152N4
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 123
Inclusion Criteria
Women aged 18-40 years
Singleton pregnancy
Cephalic presentation
Gestational age more than 37 weeks
Appropriate pelvic examination
Intact membranes
Fetal weight between 90-10th percentile estimated by ultrasound
ishop score less than or equal to 6
Exclusion Criteria
Birth history equal to or more than 3
Blood pressure equal to or greater than 140/90 mmHg
Proteinuria or preeclampsia
Getational diabetes
Unreliability of fetal heart trace or any fetal distress
Polyhydramnios or oligohydramnios
The possibility of fetal macrosomia
Intrauterine fetal death
Previous history of uterine surgery
Bleeding
Placenta previa
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to reach active labour phase. Timepoint: Immediately after intervention. Method of measurement: Physical examination.
- Secondary Outcome Measures
Name Time Method Time to delivery. Timepoint: Between intervention and delivery. Method of measurement: Clinical examination.;Percentage of cesarean section. Timepoint: 24 hours after intervention. Method of measurement: Clinical assessment.;Neonatal apgar. Timepoint: First and fifth minutes after delivery. Method of measurement: clinical assessment.