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临床试验/NCT04448782
NCT04448782已完成不适用

Characterization of Reverse Triggering and Other Asynchronies in COVID-19 Patients Under Invasive Mechanical Ventilation

Corporacion Parc Tauli1 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2020年3月9日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
32
试验地点
1
主要终点
Incidence and pattern of presentation of Reverse triggering in COVID-19 patients under invasive mechanical ventilation

研究概览

简要总结

Prospective observational trial in patients admitted to ICU diagnosed with COVID-19 requiring invasive mechanical ventilation. Characterization of Reverse Triggering asynchrony during the first 5 days of invasive mechanical ventilation and other asynchronies, and its correlation with different outcomes.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients under invasive mechanical ventilation more than 24 hours and with a minimum of 48 hours of respiratory signals registered from the ventilator
  • Diagnosis of COVID-19

排除标准

  • less than 48 hours of data,
  • age < 18 years
  • admitted from other centers under invasive mechanical ventilation.

结局指标

主要结局

Incidence and pattern of presentation of Reverse triggering in COVID-19 patients under invasive mechanical ventilation

时间窗: during the 5 first days of invasive mechanical ventilation

To analyze the incidence of Reverse Triggering in the initial phases of invasive mechanical ventilation in COVID-19 patients

次要结局

  • Incidence of Reverse Triggering related to the level of sedation in COVID-19 patients under invasive mechanical ventilation(From the day of mechanical ventilation initation up to 5 days or the last day of mechanical ventilation)
  • Incidence and pattern of presentation of asynchronies in COVID-19 patients under invasive mechanical ventilation(Each day from the day of mechanical ventilation initiation until the day of mechanical ventilation withdrawal or up to 28 days)
  • Reverse triggering and secondary asynchronies in COVID-19 patients under invasive mechanical ventilation(From the day of mechanical ventilation initiation up to 5 days)
  • Influence of asynchronies in different outcomes in in COVID-19 patients under invasive mechanical ventilation(Each day from the day of mechanical ventilation initiation until the end of invasive mechanical ventilation, ICU discharge and hospital discharge or up to 28 days)

研究者

发起方
Corporacion Parc Tauli
申办方类型
Other
责任方
Principal Investigator
主要研究者

Candelaria de Haro

Medical Doctor

Corporacion Parc Tauli

研究点 (1)

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