The Effects of Secondary Smoking During One Lung Ventilation

Not Applicable

Completed

• Conditions: Smoking; Oxygen Deficiencies
• Interventions: Other: One Lung Ventilation

• Registration Number: NCT03006224
• Lead Sponsor: Inonu University

Brief Summary

Smoking and perhaps secondary smoking is associated with many perioperative and postoperative complications, especially respiratory events. Hypoxemia and airway damage can be associated with secondary smoking. The aim of study is to predict the incidence of hypoxemia and airway damage during one lung ventilation for lobectomy.

Detailed Description

Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube will be included in this study. These patients will be divided into 2 groups. Groups S which will be included non smoking and secondary smoking and group SS which will be included secondary smoking ( smoking near him more than 10 cigarettes per day fore more than 5 years). Intra and postoperative arterial oxygen tension, arterial carbon dioxide tension and intraoperative peak airway pressure will be compared between the two groups.

Study Timeline

• Study Start: 2016-12
• Study First Submitted: 2016-12-22
• Study First Submitted QC: 2016-12-27
• Study First Posted: 2016-12-30
• Primary Completion: 2017-02
• Status Verified: 2017-04
• Study Completion: 2017-04-04
• Last Update Submitted: 2017-04-04
• Last Update Posted: 2017-04-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

• Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube, ASA physical status 2 and 3.

Exclusion Criteria

• Recent chest infection, morbid obesity, renal, hepatic and ischemic hearts disease, asthma.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group S (non smoking and secondary smoking)	One Lung Ventilation	I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.
Group SS (secondary smoking)	One Lung Ventilation	I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.

Primary Outcome Measures

Name	Time	Method
intraoperative peak airway pressure	during intraoperative ventilation
arterial oxygen tension	From beginning of Anesthesia to 1st day of surgery
arterial carbon dioxide tension	From beginning of Anesthesia to 1st day of surgery