The Effects of Secondary Smoking to Intraoperative Arterial Oxygen Tension During One Lung Ventilation in Lobectomy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Smoking
- Sponsor
- Inonu University
- Enrollment
- 60
- Primary Endpoint
- intraoperative peak airway pressure
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Smoking and perhaps secondary smoking is associated with many perioperative and postoperative complications, especially respiratory events. Hypoxemia and airway damage can be associated with secondary smoking. The aim of study is to predict the incidence of hypoxemia and airway damage during one lung ventilation for lobectomy.
Detailed Description
Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube will be included in this study. These patients will be divided into 2 groups. Groups S which will be included non smoking and secondary smoking and group SS which will be included secondary smoking ( smoking near him more than 10 cigarettes per day fore more than 5 years). Intra and postoperative arterial oxygen tension, arterial carbon dioxide tension and intraoperative peak airway pressure will be compared between the two groups.
Investigators
Ahmet Selim Ozkan
M.D.
Inonu University
Eligibility Criteria
Inclusion Criteria
- •Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube, ASA physical status 2 and 3.
Exclusion Criteria
- •Recent chest infection, morbid obesity, renal, hepatic and ischemic hearts disease, asthma.
Outcomes
Primary Outcomes
intraoperative peak airway pressure
Time Frame: during intraoperative ventilation
arterial oxygen tension
Time Frame: From beginning of Anesthesia to 1st day of surgery
arterial carbon dioxide tension
Time Frame: From beginning of Anesthesia to 1st day of surgery