Probiotics for Athlete's Recovery and Immune System
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 16
- 主要终点
- lymphocyte subpopulation total T (CD3+)
研究概览
简要总结
Overloading is a key training principle used by athletes and coaches to improve physical performance. Intensified training periods are therefore commonly incorporated into the course of a regular training season. From a clinical point of view, very intense periods of training are associated with a temporary immunological deficiency which can lead to teh "overreaching syndroms".
During periods of overreaching, nutritional strategies are mainly aimed at ensuring sufficient amounts of energy to support the increase in effort. However less is known about nutritional supplements to attenuated the inflammatory/immunological response to training stress.
Probiotic bacteria are defined as live food ingredients beneficial to the host's health. Numerous health benefits have been attributed to probiotics, including effects on gastrointestinal tract function and disease, immune function, hyperlipidemia, hypertension, and allergic conditions. Studies in the literature on the ergogenic effect of probiotics in athletes are still scarce today. this study aims to explore the potential role of probiotics on performance, recovery from fatigue and immune function during intensive period of training.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 25-55 years
- •Body mass index:> 18 and <30 kg / m2
- •Stable body weight for at least 3 months
- •regular practice of physical activity for at least 2 years
排除标准
- •Chronic diseases (cardiovascular, hepatic, respiratory, cancer)
- •Acute inflammatory states, infections or other pathologies
- •Regular use of probiotics
- •Use or treatment with steroids (within the previous 3 months)
结局指标
主要结局
lymphocyte subpopulation total T (CD3+)
时间窗: Change from baseline to up to 15 days
lymphocyte subpopulation: total T (CD3+) %
T-helper (CD4+)
时间窗: Change from baseline to up to 15 days
lymphocyte subpopulation: T-helper (CD4+) %
T-suppressor (CD8+)
时间窗: Change from baseline to up to 15 days
lymphocyte subpopulation: T-suppressor (CD8+) %
次要结局
未报告次要终点