Effects of Parenteral Protein Concentrations in Critically Ill Patients in Icu (Comparative Study)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- hand grip strength
研究概览
简要总结
Sixty patients who need Parenteral nutrition for more than 48h will be assigned into two groups .Group A (n=30) patient will receive 1g/kg/day protein and group B n=30) patient will receive 2g /kg/day. In both groups caloric requirement will be fixed at 25- 30 kcal /kg/d.
详细描述
In this study after obtaining approval from our hospital ethics committee, a written informed consent will be obtained from patient's next of kin.
Sixty patients who need PN for more than 48h will be assigned into two groups .Group A (n=30) patient will receive 1g/kg/day protein and group B n=30) patient will receive 2g /kg/day. In both groups caloric requirement will be fixed at 25- 30 kcal /kg/d.
Inclusion criteria:
Age: from 18 to 60 years Sex : male or female Predicted to be in icu ≥ 48 hs Predicted to have PN for> 48 hs.
Exclusion criteria:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: from 18 to 70 years Sex : male or female Predicted to be in icu ≥ 48 hs Predicted to have PN for> 48 hs.
排除标准
- •- Hepatic patients Renal patients Age <18 years
研究组 & 干预措施
Group A
patients received 1 g/ kg of protein
干预措施: parenteral protein 1 g/kg (Dietary Supplement)
Group B
patients received 2 g/ kg of protein
干预措施: Parenteral nutrition 2 g/kg (Dietary Supplement)
结局指标
主要结局
hand grip strength
时间窗: 10 days
hand grip strength using dynamometer
次要结局
- nitrogen balances(10 days)
- ultrasound guided muscle thickness(10 days)
研究者
Karim Naser Hasan
assisstant lecturer
Minia University