NCT05080816已完成不适用
Effects of Parenteral and Enteral Nutrition on Skeletal Muscle Genomics
Göteborg University2 个研究点 分布在 1 个国家目标入组 39 人开始时间: 2017年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 39
- 试验地点
- 2
- 主要终点
- Muscle protein metabolism
研究概览
简要总结
The study investigates effects related to muscle protein metabolism at provision of Parenteral or enteral nutrition
详细描述
Randomized study investigation alterations in muscle protein metabolism at provision of parenteral or enteral (oral drink) nutrition. The study uses a genomic/transcriptomic/proteomic approach to evaluate factors related to activation of skeletal muscle protein synthesis and protein degradation. Patients scheduled for major gastrointestinal surgery are included. Muscle specimens are collected during surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
盲法说明
Persons responsible for genomic/transcriptomic/proteomics analyses are blinded. All samples are coded.
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Major gastrointestinal surgery.
- •Assumed need of post-operative nutrition support.
排除标准
- •Insulin dependent diabetes.
- •Steroid medication.
结局指标
主要结局
Muscle protein metabolism
时间窗: ~12-14 hours.
Alterations in skeletal muscle gene expression quantified by microarray
次要结局
未报告次要终点
研究者
研究点 (2)
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