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Clinical Trials/NCT02917252
NCT02917252CompletedNot Applicable

Ketone Bodies Ingested Orally Alter Metabolism for Glucose, Lipid, and Protein

University of Aarhus1 site in 1 country6 target enrollmentStarted: February 1, 2017Last updated:
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Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
6
Locations
1
Primary Endpoint
3-hydroxybuturate
Study OverviewStudy DesignEligibility CriteriaArms & InterventionsOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

This study evaluate the metabolic effects of orally ingested ketone bodies. The study is conducted as a randomized, cross over study.

Detailed Description

Subject participate for two separate days; i) intervention, ii) placebo. Intervention: subjects drink ketone body solution. Tracer kinetics on glucose and lipid metabolism is applied. Muscle tissue and adipose tissue biopsies are taken.

Placebo: subjects drink saline. Same sampling as on intervention day.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Basic Science
Masking
Single (Participant)

Eligibility Criteria

Ages
18 Years to 40 Years (Adult)
Sex
Male
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •BMI 20-30

Exclusion Criteria

  • •alcohol or drug abuse
  • •Critically ill

Arms & Interventions

Intervention

Active Comparator

Subjects drink 3-hydroxybuturate

Intervention: 3-hydroxybuturate (Other)

Placebo

Placebo Comparator

Subjects drink saline

Intervention: Placebo (Other)

Outcomes

Primary Outcomes

3-hydroxybuturate

Time Frame: 0-270 minutes

blood level of 3-hydroxybuturate

Secondary Outcomes

  • Glucose(0-270 minutes)
  • lipid metabolism(0-270 minutes)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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