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Protein feeding prior to sleep as a dietary strategy to improve post-exercise recovery and muscle mass in young and elderly men.

Recruiting
Conditions
1. Sport recovery enhancement2. Sarcopenia
Registration Number
NL-OMON27673
Lead Sponsor
TI Food & NutritionMaastricht University Medical Centre+
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
98
Inclusion Criteria

1. Males;

2. Age: Between 18-35 or 65-85 yr;

Exclusion Criteria

1. Smoking;

2. Type 2 diabetic;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome is muscle protein synthesis fractional synthetic rate (FSR). By taking a muscle biopsy prior to and just after sleep, muscle enrichments of amino acid tracer can be measured and used to calculate rate of muscle protein synthesis (FSR). Amino acid tracers will be provided by intravenous (IV) infusion and by intrinsically–labelled protein.
Secondary Outcome Measures
NameTimeMethod
The secondary outcome is amino acid absorption and digestion kinetics. The use of intrinsically labelled protein and blood draws allows us to assess the rate of appearance of the tracer in the plasma as a measurement of amino acid absorption and digestion.
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