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Clinical Study to evaluate the Efficacy and Safety of MEZO cream with ELOCON Cream in the treatment of plaque psoriasis

Phase 3
Completed
Conditions
Health Condition 1: L00- Staphylococcal scalded skin syndrome
Registration Number
CTRI/2019/11/021908
Lead Sponsor
AGIO PHARMACEUTICALS LTD
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
60
Inclusion Criteria

Adults of both sexes

Age 18 or older with good mental health

Psoriasis patients with mild to moderate as classified by investigator based on body surface area

Mild to moderate psoriasis means that the red scaly patches plaques cover less than 10 percent of your body

Subject who in the opinion of the investigator are free of any medical condition s that may interfere with study participation or affect study measures

Willing to provide written informed consent for participation in the study and adhere to the protocol requirements

Patients who agreed to return for follow-up visits

Exclusion Criteria

Patients who are not willing to give written informed consent

Patients who also had psoriatic plaques of skin disorders caused by fungi or bacteria and they were making use of antibiotic or antifungal

Other types of skin damage that was not psoriasis

Pregnant and nursing women

Patients using oral anticoagulants

Any finding of clinical observation that is interpreted by the investigator as a risk to the patients participation in the study

7.Severely immune compromised patients

Use of any investigational drug currently or within 30 days prior to study entry

Subjects on any prescription medication that might interfere with study outcomes

History of alcohol or drug abuse

Patients having Impetigo cellulitis lymphangitis

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess the improvement in psoriatic sign and symptoms using a scale <br/ ><br>Parameters will be evaluated for erythema plaque size Scaling itching thickness of the lesionTimepoint: baseline EOT
Secondary Outcome Measures
NameTimeMethod
Self Assessment of General Health <br/ ><br>Tolerance <br/ ><br>To evaluate the quality of life <br/ ><br>Assessment of safety of the Investigational products <br/ ><br>Adverse event <br/ ><br>Physical examination <br/ ><br>Biomarker of systemic safety <br/ ><br> Hematological test <br/ ><br>Liver function test <br/ ><br>Renal function test Serum creatinine <br/ ><br>RBS <br/ ><br>Timepoint: baseline to EOT
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