Correlation of cytological and histo pathological findings in bone lesions :A cross sectional study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- To classify the bone lesions on the basis of cyto-histomorphological features as per
研究概览
简要总结
The study will be conducted in Department of Pathology in collaboration with Department of Orthopaedics, Rohilkhand Medical College and Hospital, Bareilly after taking approval from Institutional Ethics Committee and with consent from patient will include all cytological and biopsy specimens of bone lesions received in department in one year duration
PROCEDURE OF FNAC
The informed consent to be taken from the patient as per standard protocol.
The patient’s demographic data including gender, age, comorbid conditions and clinical history such as pain, swelling and relevant radiological investigation record will be maintained
The patient will be explained the details of the procedure, and written consent will be documented.
A thorough clinical examination will be conducted on the patient and details about the lesion or lump (including site, size, consistency, mobility, and tenderness) will be noted.
The procedure (FNA) will be performed under strict aseptic precautions, with prepacked swabs soaked in 70% alcohol.
A sterile needle of 20-21 gauge attached to 20 cc disposable syringe mounted in a syringe holder will be positioned above the superficial lesion and advanced gently to puncture the skin.
Using two fingers of the other hand to keep the lump fixed, the needle will be advanced into the lesion
When sure that the needle tip is inside the target tissue, the plunger will be pulled to apply negative pressure.
Multiple passes will be made without exiting the tissue and the needle moved back and forth in different directions to collect sufficient material.
With the needle still in the target tissue, the negative pressure will be released. The needle will then be withdrawn from the lesion.
Subsequently, the needle will be detached, and air will be drawn into the syringe.
After reattachment of the needle to the syringe, the material will be blown onto several clean glass slides, and smeared using a spreader.
The gross appearance of the aspirate will be recorded.
The slides will be air-dried and stained with Leishman-Giemsa
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •ALL CASES OF BONE LESIONS WHO WILL UNDERGO BOTH HISTOPATHOLOGY AND CYTOPATHOLOGY.
排除标准
- •BIOPSIES REPORTED AS UNSATISFACTORY FOR EVALUATION CYTOLOGICAL SAMPLES ONLY HAVING BLOODY ASPIRATE.
结局指标
主要结局
To classify the bone lesions on the basis of cyto-histomorphological features as per
时间窗: 4 weeks
WHO classification (2020).
时间窗: 4 weeks
To categorize the bone lesions on the basis of age, gender and site. To correlate cytological findings with histopathological findings.
时间窗: 4 weeks
次要结局
- To classify the bone lesions on the basis of cyto-histomorphological features as per(WHO classification (2020).)
研究者
Dr Tavleen Bedi
Rohilkhand medical college and hospital, Pilibhit bypass road, Bareilly