Cardiovascular Imaging and Biomarker Analyses (CIBER)
试验速览
- 阶段
- 不适用
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Biomarker levels before cardiac imaging
研究概览
简要总结
"Cardiovascular Imaging and Biomarker Analyses (CIBER)" is a single-center, prospective and observational study evaluating the expression of novel biomarkers in patients undergoing cardiacvascular imaging within clinical routine care. It is aimed to evaluate associations with biomarker expressions with ascertained cardiac imaging parameters.
详细描述
"Cardiovascular Imaging and Biomarker Analyses (CIBER)" is a single-center, prospective and observational study evaluating the expression of novel biomarkers in patients undergoing cardiacvascular imaging within clinical routine care. It is aimed to evaluate associations with biomarker expressions with ascertained cardiac imaging parameters. Furthermore the prognostic value of biomarkers and imaging parameters on mid-term and long-term prognosis will be evaluated. Novel biomarkers will comprise blood derived biomarkers including neurohormones, proteins, cytokines, microRNAs and metabolomics.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with low to intermediate risk for coronary artery disease
排除标准
- •under 18 years
- •mechanical heart valve
- •pulmonary embolism
- •deep vein thrombosis
- •myocardial infarction within the last 3 months
- •electrical cardioversion within 30 days
- •status after heart transplant
- •transient ischemic attack (TIA) or stroke within last 30 days
- •intracerebral bleeding within the last 2 months
- •acute infection
- •existing or planned pregnancy
- •chronic kidney disease with eGFR < 40 ml/min
结局指标
主要结局
Biomarker levels before cardiac imaging
时间窗: 24 hours before cardiac imaging
次要结局
未报告次要终点
研究者
Michael Behnes
Dr. med
Universitätsmedizin Mannheim