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Clinical Trials/NCT01063504
NCT01063504
Completed
Phase 2

Teriparatide for Improved Knee Prosthesis Fixation

University Hospital, Linkoeping1 site in 1 country60 target enrollmentFebruary 2010
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ConditionsOsteoarthritis of the Knee
Interventionsteriparatide
Drugsteriparatide

Overview

Phase
Phase 2
Intervention
teriparatide
Conditions
Osteoarthritis of the Knee
Sponsor
University Hospital, Linkoeping
Enrollment
60
Locations
1
Primary Endpoint
Migration as measured by RSA maximal total point motion.
Status
Completed
Last Updated
12 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSitesSimilar Trials

Overview

Brief Summary

The investigators will study how well knee joint prostheses become fixed to the bone when patients get teriparatide, compared to placebo. Measurements will use high resolution 3D radiography (radiostereometry, RSA).

Registry
clinicaltrials.gov
Start Date
February 2010
End Date
June 2013
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Hospital, Linkoeping
Responsible Party
Principal Investigator
Principal Investigator

Per Aspenberg

professor

University Hospital, Linkoeping

Eligibility Criteria

Inclusion Criteria

  • •Osteoarthritis of the knee planned for prosthesis surgery

Exclusion Criteria

  • •Poor health, drugs affecting bone metabolism.

Arms & Interventions

Teriparatide 20 microgram daily for 2 months

Intervention: teriparatide

Placebo

Intervention: teriparatide

Outcomes

Primary Outcomes

Migration as measured by RSA maximal total point motion.

Time Frame: 2 years

Study Sites (1)

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