NCT01063504已完成2 期
Teriparatide for Improved Knee Prosthesis Fixation
University Hospital, Linkoeping1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2010年2月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Migration as measured by RSA maximal total point motion.
研究概览
简要总结
The investigators will study how well knee joint prostheses become fixed to the bone when patients get teriparatide, compared to placebo. Measurements will use high resolution 3D radiography (radiostereometry, RSA).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Osteoarthritis of the knee planned for prosthesis surgery
排除标准
- •Poor health, drugs affecting bone metabolism.
研究组 & 干预措施
Teriparatide 20 microgram daily for 2 months
Active Comparator
干预措施: teriparatide (Drug)
Placebo
Placebo Comparator
干预措施: teriparatide (Drug)
结局指标
主要结局
Migration as measured by RSA maximal total point motion.
时间窗: 2 years
次要结局
未报告次要终点
研究者
Per Aspenberg
professor
University Hospital, Linkoeping
研究点 (1)
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