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Clinical Trials/NCT02346019
NCT02346019
Completed
N/A

Thighplasty of Transfemoral Amputee Residual Limbs to Improve Prosthesis Fit and Patient Functional Outcomes

Shirley Ryan AbilityLab1 site in 1 country1 target enrollmentAugust 2014

Overview

Phase
N/A
Intervention
Not specified
Conditions
Transfemoral Amputees
Sponsor
Shirley Ryan AbilityLab
Enrollment
1
Locations
1
Primary Endpoint
Assess compliance of residual limb in the socket, which will improve the fit and comfort of the prosthesis.
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The purpose of our study is to improve the fit and function of prosthetic sockets for above the knee amputees through the use of an outpatient thigh reduction surgical procedure.

Detailed Description

We will quantify the anatomical distribution of subcutaneous fat, muscle and bone in the residual limb of the transfemoral amputees with an MRI. We will measure the displacement of the socket wall relative to the femur under mechanical loading with x-ray. The functional mobility level of the subject with be quantified via standard clinical and bio mechanical tests. Perform a standard medial thighplasty with our without thigh liposuction. Characterize the post-surgical anatomy, compliance of the residual limb and function of the amputee subjects. After six months, repeat the MRI and xray and compare results. Subject will also complete a questionnaire regarding their views on the outcome of the surgery.

Registry
clinicaltrials.gov
Start Date
August 2014
End Date
March 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Todd Kuiken

Director, Center for Bionic Medicine

Shirley Ryan AbilityLab

Eligibility Criteria

Inclusion Criteria

  • Obese transfemoral amputees with a BMI of at least
  • Mid to long residual limb, excessive adipose tissue in their residual limb
  • Community ambulators
  • Adults over the age of 18

Exclusion Criteria

  • Amputation due to vascular disease or diabetes
  • Cognitive impairments that would interfere with the protocol or patient safety
  • Systemic disease that is not stable or would significantly increase the risk of complications with surgery
  • Chronic wounds
  • People who do not ambulate on a daily basis
  • Children under the age of 18.

Outcomes

Primary Outcomes

Assess compliance of residual limb in the socket, which will improve the fit and comfort of the prosthesis.

Time Frame: Pre surgery and 6 months post surgery

We will measure the compliance of their residual limb by the displacement of the socket wall relative to the femur under mechanical loading with X-ray. The subjects will adjust their foot placement, limb loading and muscle contractions to achieve up to 8 specified force/torque levels (as measured by a 6 degree-of-freedom load cell located in series with their pylon and socket), which correspond to forces and torques that are typical of over ground walking and standing postures and are scaled for their body weight. For each force/torque level, static X-ray scans of locations of the prosthetic socket wall and residual limb femur will be acquired.

Secondary Outcomes

  • Assess walking endurance(Pre surgery and 6 months post surgery)
  • Assess balance stability(Pre surgery and 6 months post surgery)

Study Sites (1)

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