Preventing Postpartum Depression in Adolescent Mothers
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postpartum Depression
- Sponsor
- Women and Infants Hospital of Rhode Island
- Enrollment
- 250
- Locations
- 1
- Primary Endpoint
- Diagnosis of depression
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The Specific Aim of this study is to conduct a randomized controlled trial to evaluate whether Project REACH (an interpersonal psychotherapy-based intervention) compared with a didactic attention-control program reduces the risk of PPD in adolescent mothers.
Primary Hypothesis:
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The intervention (Project REACH) will be significantly more efficacious than the control program in reducing the risk of PPD up to six months postpartum in adolescent mothers.
Secondary Hypotheses:
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The decreased rate of major depression in the Project REACH group compared to the control program group will be sustained through one year postpartum.
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Adolescent mothers in Project REACH compared to the control program group will have higher levels of maternal-child bonding.
Detailed Description
Each year, more than 400,000 births in the United States are to mothers less than 20 years old. Alarmingly, approximately 25-36% of teen mothers experience postpartum depression (PPD), a condition associated with significant social and health morbidity. PPD places teen mothers and their children at great risk during an already challenging time in their lives. Preventing PPD in this vulnerable population is essential to improving overall health. Project REACH is a randomized controlled trial, to evaluate whether our novel preventive intervention compared to a didactic attention control reduces the risk of PPD in adolescent mothers. The intervention, REACH (Relax, Encourage, Appreciate, Communicate, Help), is based on Interpersonal Psychotherapy (IPT) and targets those factors that may play a significant role in the development of PPD in adolescent mothers (i.e., poor social support, role transitions and life stressors). The control condition includes didactic prenatal education sessions. Project REACH builds on the foundation of our NIMH-funded treatment development project and pilot study (R34 MH077588). The pilot study demonstrated feasibility, acceptability and initial efficacy in a small sample. The current R01 proposal aims to evaluate the efficacy of the Project REACH intervention in reducing the risk of PPD.
Investigators
maureen phipps
Study Principal Investigator
Women and Infants Hospital of Rhode Island
Eligibility Criteria
Inclusion Criteria
- •Less than 24 weeks pregnant
- •Not currently being treated for depression
- •Speaks and reads English fluently
Exclusion Criteria
- •Currently receiving mental health services from a health care provider
- •Meets DSM-IV criteria for an affective disorder, substance use disorder, or psychosis
Outcomes
Primary Outcomes
Diagnosis of depression
Time Frame: within 6 months postpartum
Outcome assessment using KID-SCID
Secondary Outcomes
- Degree of depressive symptoms(pre-randomization; 34-36 weeks gestation; within 4 days postdelivery; postpartum weeks 6, 12, 24 and 52)