PRimary Prevention Of Depression in Offspring of Depressed Parents

Not Applicable

Completed

• Conditions: Depression
• Interventions: Behavioral: Prevention programme

• Registration Number: NCT02115880
• Lead Sponsor: Ludwig-Maximilians - University of Munich

Brief Summary

The purpose of this randomised controlled trial is to see whether a group-based psychological intervention for families can reduce the inflated risk of depression in children and adolescents who have at least one parent who suffers from depression (or who has suffered from depressed in the child's lifetime).

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-04-07
• Study First Submitted QC: 2014-04-14
• Study First Posted: 2014-04-16
• Study Start: 2014-05
• Primary Completion: 2019-02
• Study Completion: 2019-02
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-12
• Last Update Posted: 2023-12-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• At least one parent who meets diagnostic criteria for a current (or past, during the child's lifetime) diagnosis of depression
• The participating child is aged 8-17
• The participating child has an IQ of at least 85
• Both child and parent(s) have adequate German-language skills
• Both child and parents consent to intervention sessions being video-recorded

Exclusion Criteria

• The participating parent(s) has current symptoms of bipolar disorder, psychotic symptoms, personality disorder, substance addiction, or is suicidal
• The participating child meets criteria for a current, or previous, episode of any psychiatric disorder
• The participating child is undergoing or has undergone treatment for depression
• The participating child or parent have serious symptoms of a disorder (or are in crisis) that may hamper their ability to take part in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Prevention programme	Prevention programme	-

Primary Outcome Measures

Name	Time	Method
Presence or absence of a depressive episode (child)	T4 (9 months after completion of the programme)	The German version of the Diagnostic Interview for Psychiatric Disorders in Children and Adolescents (Kinder DIPS) will be used to assess whether the child meets the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria for a depressive episode.

Secondary Outcome Measures

Name	Time	Method
Symptoms of depression (child)	Within 2 weeks of the last session of the intervention (T2) as well as 3 months after the intervention (T3) and 9 months after the intervention (T4)	Self-reported symptoms of depression will be collected using the German questionnaires "Depression Inventory for Children and Adolescents" (DIKJ) and Beck Depression Inventory (BDI-II; depending on the child's age).
Psychopathological symptoms (child)	Within 2 weeks of the last session of the intervention (T2) as well as 3 months after the intervention (T3) and 9 months after the intervention (T4)	More general internal and external psychopathological symptoms will be measured using German versions of the questionnaires "Youth Self-Report" (YSR; child self-report) and "Child Behaviour Checklist" (CBCL; parent-report).

Trial Locations

Locations (1)

Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy; 🇩🇪 Munich, Bavaria, Germany