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Clinical Trials/NCT04444583
NCT04444583
Completed
Not Applicable

Recognition of Heart Failure With Micro Electro-Mechanical Sensors (REFLECS) FI

Precordior Ltd2 sites in 1 country155 target enrollmentJune 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Heart Failure
Sponsor
Precordior Ltd
Enrollment
155
Locations
2
Primary Endpoint
HF specific motion sensor characteristics validation against echocardiography and other clinical features
Status
Completed
Last Updated
9 months ago

Overview

Brief Summary

In this study the ability of smartphone sensors (accelerometer and gyroscope) to identify patients with heart failure will be studied.

Detailed Description

Heart Failure (HF) is a condition where heart is unable to maintain adequate volume of blood in circulation corresponding to prevailing physiological demand. Gyrocardiography is a technique that utilizes micro electromechanical sensors (MEMS), accelerometer and gyroscope, to detect vibrations and rotation of thorax caused by cardiac motion. The main purpose of this study is to test the ability of an app of a smartphone with embedded motion sensors, positioned on the chest which measures the movements and function of the heart, to identify patients with different types of heart failure and their characteristics, as compared with clinical diagnosis. Echocardiography will also be used to confirm changes in cardiac cardiac mechanics including strain, cardiac torsion, diastolic filling characteristics.

Registry
clinicaltrials.gov
Start Date
June 1, 2020
End Date
December 31, 2024
Last Updated
9 months ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Precordior Ltd
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age \>18 years
  • Patients visiting hospital for heart failure, either outpatient clinic or cardiac ward
  • Signed informed consent as an acceptance to participate to the trial

Exclusion Criteria

  • Age \<18 years
  • Severe cardiac valve disease
  • Previous prosthetic cardiac valve
  • Major adverse cardiovascular event or surgery within 6 weeks of planned study enrollment
  • Patients with pacemaker
  • Informed consent form not signed.

Outcomes

Primary Outcomes

HF specific motion sensor characteristics validation against echocardiography and other clinical features

Time Frame: From the hospital admission to study closure visit, on average 15 weeks

The study aims to validate HF specific characteristics obtained with accelerometer (m/s2) and gyroscope (degree/s) against the current gold standard, detailed echocardiography examination in individuals already diagnosed with HF. Data of anonymised subjects without diagnosed or suspected HF will be used as controls to study the detection of HF.

Secondary Outcomes

  • HF decompensation specific motion sensor characteristics validation(14 weeks)

Study Sites (2)

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