Prodromal Alpha-Synuclein Screening in Parkinson’s Disease Study
Recruiting
- Conditions
- G20.0
- Registration Number
- DRKS00021426
- Lead Sponsor
- niversitätsklinikum Schleswig-Holstein Campus Kiel
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 2000
Inclusion Criteria
(I) Capacity for consent (in case of doubt verified by two independent neurologists), (II) written informed consent, (III) age = 50 years
Exclusion Criteria
(I) Presence of clinical PD at the time of study inclusion, (II) other significant neurologic diseases affecting the central nervous system (e.g. Multiple sclerosis), (III) other significant diseases e.g. orthopaedic diseases affecting quantitative motor assessment; (IV) in case of participation in the lumbal puncture substudy: contraindications for the performance of lumbal puncture (bleeding tendency, intake of anticoagulants)
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Extend and progression of risk marker profile
- Secondary Outcome Measures
Name Time Method Development and progression of non-motor and motor symptoms