comparing IVF results in two GnRH antagonist protocols and Stop protocol (GnRH agonist/antagonist) in patients with polycystic ovary syndrome
Not Applicable
- Conditions
- infertility.Female infertility
- Registration Number
- IRCT20180409039247N8
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
PCO patients according to Rotterdam criteria
Age 20 to 35 years
Infertility > 1 year
Sperm analysis is normal or has the minimum necessary criteria for ICSI
AMH above 5
Exclusion Criteria
History of autoimmune diseases, coagulation disorders, uterine anomalies, chromosomal and genetic disorders, chronic renal and metabolic diseases, hypo and hyperthyroidism, history of malignancy, endometriosis, history of repeated miscarriage and repeated implantation failure
Pharmaceutical reaction to ovulation stimulation drugs
Lack of follicle growth suitable for puncture
The patient's lack of consent to complete the treatment course
Severe Oligoastenoteratospermia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of follicles above 16 mm, the degree of follicle synchrony, the number and quality of obtained oocytes (metaphase 1, 2 and GV). Timepoint: The examination will be cross-sectional on the day of oocyte puncture. Method of measurement: Questionnaire for demographic information and patient records, ultrasound to check follicles and embryology laboratory information to check the number and quality of oocytes and embryos.
- Secondary Outcome Measures
Name Time Method umber and quality of embryos. Timepoint: On the day of ovarian puncture. Method of measurement: It is determined by the embryologist three days after the puncture.