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Comparison of IVF outcomes in two GnRH-antagonist and Stop GnRH-agonist/GnRH-antagonist protocols in patients with poor ovarian response

Not Applicable
Conditions
infertility.
Female infertility
Registration Number
IRCT20180409039247N10
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Female
Target Recruitment
60
Inclusion Criteria

POR patients according to the Bologna criteria: old age (40 years) or any other risk factor for POR such as endometriosis and ovarian surgery, autoimmune diseases and genetic problems
Achieving =3 oocytes with the gnrh antagonist stimulation protocol in the previous cycle
Abnormality of ovarian reserve tests (AFC<3-5, AMH<0.5-1.1 ng) in the absence of old age of the mother or abnormality of ovarian reserve
BMI below 27
Sperm analysis is normal or has the minimum necessary criteria for ICSI

Exclusion Criteria

History of autoimmune diseases, coagulation disorders, uterine anomalies, chromosomal and genetic disorders, chronic renal and metabolic diseases, hypo and hyperthyroidism, history of malignancy, endometriosis
recurent pregnancy loss
recurrent implantation failure

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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