Evaluation of GnRH long-acting agonist protocols and GnRH antagonist protocol in controlled ovarian stimulation in in vitro fertilization in infertile women with poor ovarian response
Phase 3
Recruiting
- Conditions
- Infertility.Female infertility
- Registration Number
- IRCT20110509006420N28
- Lead Sponsor
- Yazd University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 170
Inclusion Criteria
IVF/ICSI candidates
Women who respond poorly to ovulation stimulation: ovarian reserve less than 1.2 ng/ml and AFC number less than 5 POSEIDON group 3-4
Women between the ages of 18 and 45
Exclusion Criteria
Asherman's history
Severe uterine adenomyosis
Egg donation cycles
Cases of severe male infertility (azoospermia)
Cases where surrogacy is used
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: sonography.
- Secondary Outcome Measures
Name Time Method The number of embryos with qualities of A,B,or C. Timepoint: En 1-2 days after ovarian puncture. Method of measurement: Microscopic manual counting by embryologist.;En The duration of controlled ovarian stimulation period. Timepoint: Immediatly after controlled ovarian stimulation. Method of measurement: Time scale(day).;The dosage of Gonadotropin used. Timepoint: After controlled ovarian stimulation. Method of measurement: Counting.;Chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: pregnancy test.;Implantation. Timepoint: After a positive pregnancy test. Method of measurement: sonography.