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Comparison of two drugs for luteal phase support in IVF cycles

Not Applicable
Completed
Conditions
Health Condition 1: N979- Female infertility, unspecified
Registration Number
CTRI/2020/02/023552
Lead Sponsor
All India Institute of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
69
Inclusion Criteria

1. FSH less than and equal to 12 IU/L

2. AMH more than and equal to 1.5 ng/ml

3. BMI 18 to 30 Kg/ m2

4. E2 more than 2500 pg/ml on the day of ovulation trigger

Exclusion Criteria

1. More than and equal to 2 Previous IVF failures

2. Endometriosis

3. Hydrosalpinges (unilateral/bilateral)

4. Uterine factor unfavorable for implantation (adenomyosis, intrauterine adhesions, thin

endometrium, fibroids)

5. More than 20 oocytes retrieved

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
clinical pregnancy rate <br/ ><br>Timepoint: To compare GnRH agonist with low dose hCG for luteal phase support among GnRH <br/ ><br>agonist triggered antagonist cycles in terms of clinical pregnancy rate <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
1. Hormonal dynamics (E2,P4,LH) after oocyte retrieval <br/ ><br>2. Implantation Rate <br/ ><br>3. Ongoing pregnancy rate <br/ ><br>4.OHSS rate <br/ ><br>5.Miscarriage rate <br/ ><br>Timepoint: 2 years
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