The role of GnRH analogues (medical therapy) in improving fertility in women with early stage endometriosis.
Not Applicable
Completed
- Conditions
- Health Condition 1: null- infertility due to endometriosis (minimal to mild)
- Registration Number
- CTRI/2016/08/007162
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
1.Infertile women with minimal or mild endometriosis post laparoscopic surgical treatment.
2.Age less than or equal to 36 yrs.
3.Husband with normal semen parameters
Exclusion Criteria
1.Age > 36 yrs.
2.Moderate or severe endometriosis.
3.Pelvic inflammatory disease including genital Tuberculosis.
4.Poly-Cystic Ovarian Syndrome (PCOS).
5.Endometrial polyp, Sub-mucous myoma.
6.Diminished ovarian reserve as evaluated with FSH >10 IU/ml.
7.Recurrent endometriosis.
8.Male factor infertility.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method clinical pregnancy ratesTimepoint: Confirmation of clinical pregnancy was done by presence of a viable fetus at 6 weeks by ultrasonography
- Secondary Outcome Measures
Name Time Method days of stimulationTimepoint: day of administering hCG injection.;dose of gonadotropin injectionTimepoint: calculated using vials containing 150 IU of hMG per vial;Endometrial thicknessTimepoint: greater than or equal to 7mm.;number of folliclesTimepoint: follicle size greater than or equal to 18mm.