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Effect of adding long-acting GnRH agonist plus Letrozole to frozen embryo transfer cycles

Phase 3
Recruiting
Conditions
Female infertility.
Female infertility
Registration Number
IRCT20220104053629N1
Lead Sponsor
Yazd University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
64
Inclusion Criteria

18 to 42 years old infertile women
The history of at least two implantation failure of good quality embryos (A and B)
Frozen thawed embryo transfer cycle
Candidate for embryo transfer with A and B grade

Exclusion Criteria

Severe male factor or sperm retrieval except ejaculation
Endometriosis in previous sonography or laparascopy
Severe adenomiosis in sonography
History of myoma surgery or any interfering myoma with implantatio
History of implantation failure because of thin endometrium

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Rate of chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: pregnancy blood test.
Secondary Outcome Measures
NameTimeMethod
Rate of clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: Seeing gestational sac in sonography.;Rate of chemical abortion. Timepoint: 4 weeks after embryo transfer. Method of measurement: Positive pregnancy blood test without gestational sac.
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