The effect of low dose hCG with GnRH agonist in decreasing rate of ovarian hyper stimulation syndrome in IVF cycles.
Phase 3
- Conditions
- Female infertility.Complications associated with artificial fertilization, Hyperstimulation of ovaries
- Registration Number
- IRCT2016031427045N1
- Lead Sponsor
- Vice Chancellor for Research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Infertile women with following conditions: 18-39 year old; Normal FSH level; AMH>3.5 ng/ml; Poly cystic ovary (AFC>24); Previous ovarian hyper stimulation syndrome; in the day of oocyte retrieval the number of follicles bigger than 18mm>16 or Estradiol>4000 pg/ml
Exclusion criteria: Maternal age>40 year; Hypothalamic dysfunction.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ovarian hyper stimulation syndrome. Timepoint: 2 weeks after embryonal transfer. Method of measurement: Transvaginal ultrasonography and examination.
- Secondary Outcome Measures
Name Time Method Chemical Pregnancy. Timepoint: 14 days after embryonal transfer. Method of measurement: ßhCG titration.;Implantation rate. Timepoint: 4 weeks after embryonal transfer. Method of measurement: Observationl of gestational sac in transvaginal sonography.;Clinical pregnancy rate. Timepoint: 2 weeks after positive pregnancy test. Method of measurement: Observation of gestational sac in transvaginal sonography.