Food Intake of Hospitalized Elderly and Its Influence on Muscular and Clinical Outcomes

Recruiting

• Conditions: Atrophy, Muscular; Undernutrition

• Registration Number: NCT06940284
• Lead Sponsor: University of Sao Paulo General Hospital

Brief Summary

The objectives of the present study are: 1) to characterize the energy-protein intake of the elderly during hospitalization; 2) to verify the influence of energy-protein intake during hospitalization on muscular (i.e., cross-sectional area of the rectus femoris and vastus lateralis muscles, muscle strength, functionality and level of independence) and clinical (i.e., length of hospital stay, hospital readmission and mortality) at the time of hospital discharge, 2 and 6 months after hospital discharge and; 3) to verify whether energy-protein intake during hospitalization is a significant predictor of loss of function and muscle mass, length of hospital stay, hospital readmission rate and mortality.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-04-14
• Study First Submitted QC: 2025-04-14
• Study First Posted: 2025-04-23
• Status Verified: 2025-05
• Study Start: 2025-05-01
• Last Update Submitted: 2025-05-22
• Last Update Posted: 2025-05-23
• Primary Completion: 2026-01-30
• Study Completion: 2026-01-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• both sex;
• 65 years and older;
• hospital stay less than 48 hours;

Exclusion Criteria

• cancer in the last 5 years;
• delirium;
• cognitive deficit that impossibility the patient to read and sign the informed consent form;
• neurological disease;
• neurodegenerative muscular disease;
• patients receive nutrition via enteral and parenteral routes.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vastus Lateralis Muscle Cross-sectional Area	From date of admission until the date of medical discharge. Up to 30 days.	Vastus Lateralis Muscle Cross-sectional Area will be assessed through ultrasound

Secondary Outcome Measures

Name	Time	Method
Functional independence	From date of admission until the date of medical discharge. Up to 30 days.	Functional independence will be assessed using Barthel Index. The scores range from 0 to 100. A score of 100 means the individual is fully independent, while lower scores indicate increasing levels of dependence.
Length of hospital stay	From date of admission until the date of medical discharge. Up to 30 days.	Length of hospital stay will be the time (in days) until medical discharge.
Mortality	From date of admission until the date of medical discharge. Up to 30 days.	Mortality rate in percent
Hospital readmission post-medical discharge	1- and 2- months post-medical discharge	Hospital readmission post-medical discharge will be the number of times that he is admitted in the hospital post-medical discharge.
Handgrip strength	From date of admission until the date of medical discharge. Up to 30 days.	Strength will be evaluated using handgrip strength test
Muscle function	From date of admission until the date of medical discharge. Up to 30 days.	Muscle function evaluated trough battery of test

Trial Locations

Locations (1)

University of Sao Paulo; 🇧🇷 São Paulo, SP, Brazil