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临床试验/CTRI/2024/11/076501
CTRI/2024/11/076501尚未招募不适用

Association of Menopause Duration with Neuromuscular Functions in Postmenopausal woman: A Cross-Sectional study

Jamia Millia Islamia1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年11月20日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
100
试验地点
1
主要终点
Muscle Strength

研究概览

简要总结

Menopause is described as the permanent cessation of menstrual cycles, and categorized into premenopausal, perimenopause, and postmenopausal stages. Menopause has diverse effect on women health, which ultimately decreases the quality of life. To the best of my knowledge there are very limited or no evidences regarding the association of menopause duration with neuromuscular functions in postmenopausal women. The present study seeks to investigate the association of menopause duration with neuromuscular function in postmenopausal women. It includes objective assessment of postural control, muscle strength, and cognitive function in postmenopausal women with a correlation to menopause duration and a subjective evaluation of postmenopausal severity of symptom, bladder function, anxiety, stress, depression, and physical activity related to menopause duration.

After selection for the study, Participant will be explained the purpose, methodology of the study. They will be further divided into into group 1 (Perimenopause), group 2 (women whose periods stopped 2 to 5 years ago) and group 3 (women whose periods stopped more than 5 years ago). The first session will help participant get comfortable with the study and involves filling out several questionnaires about symptoms related to the change in their monthly cycle, how active they are, any urinary issues, feelings of sadness or anxiety, stress levels, and how quality of life is during this phase of life. The second session will focus on testing the muscle strength (For grip strength they will be asked to squeeze the measuring device as hard as they can with their stronger hand, For ankle Strength: they will be asked to lie down with one leg straight, their foot will be held in place while they will try to lift it up against the device. Leg Strength Test: They will try to lift the heaviest weight they can once. If succeed, the weight will be increased for the next attempt), Balance (They will be asked to stand barefoot on a round board with a small gap between your feet. Tilt your body as far as you can in four directions: forward, backward, right, and left. The board will measure how much they tilt. For Reaction Time Test: Stand on the board and look at the screen, when a coloured spot appears on the screen, try to move to touch it as quickly as possible, The reaction time will be measured in four directions: forward, backward, right, and left) and memory (They will hear a series of numbers and need to repeat them in the same order and in reverse order).

研究设计

研究类型
Observational

入排标准

年龄范围
40.00 Year(s) 至 65.00 Year(s)(—)
性别
Female

入选标准

  • Subjects who are able to walk independently without an assistive device.
  • Normal Hearing Normal vision Able to understand the commands.

排除标准

  • History of any neurological, psychological and psychiatric disorder.
  • Alcoholism and other drug abuse Chronic Hypertension Receiving Hormonal Therapy History of Hysterectomy Subjects under antidepressants Renal or endocrine disorders.

结局指标

主要结局

Muscle Strength

时间窗: One time (on day 1)

Postural Control

时间窗: One time (on day 1)

Cognitive Function

时间窗: One time (on day 1)

次要结局

  • Severity of menopausal symptoms(Physical Activity Level)

研究者

申办方类型
Government funding agency
责任方
Principal Investigator
主要研究者

Dr Majumi M Noohu

Jamia Millia Islamia

研究点 (1)

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