Do washed irradiated red blood cells with a balanced solution improve the quality of the priming in cardiopulmonary bypass for neonates and infants?
Withdrawn
- Conditions
- Quality of red bloodcells10007593
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Neonates and infants with a bodyweight of < 20 kg
Elective heartsurgery
Exclusion Criteria
Hepatic insufficienty
Renal insufficiency
Procedures with deep hypothermic circulatory arrest
Procedures with a prolonged low flow technique
Infants with a body weight > =20 kg
Emergency procedures
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Hemoglobin, hematocrit, platelet count, potassium, sodium, chlorine, lactate,<br /><br>free hemoglobin and blood gasses will be measured by standard protocol.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Ventricular function assessment will be measured by routine intra-operative<br /><br>Tran esophageal echocardiography and by thermo dilution. Hospitalization and<br /><br>ventilation period will be noted.</p><br>
Related Research Topics
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What molecular mechanisms are involved in red blood cell washing for neonatal cardiopulmonary bypass?
How does the use of washed irradiated red blood cells compare to standard priming solutions in CPB for infants?
Are there specific biomarkers that indicate improved red blood cell quality post-washing in CPB?
What adverse events are associated with irradiated red blood cell priming in neonatal CPB and how are they managed?
What are the potential benefits of using balanced solutions in combination with washed irradiated red blood cells for CPB in neonates?