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Clinical Trials/NCT02873754
NCT02873754
Completed
Not Applicable

Mobile Health Intervention to Help Low-Income Smokers Quit Smoking and Increase Physical Activity

Duke University1 site in 1 country11 target enrollmentJanuary 2017

Overview

Phase
Not Applicable
Intervention
Cognitive Behavioral Counseling
Conditions
Smoking
Sponsor
Duke University
Enrollment
11
Locations
1
Primary Endpoint
Number of Participants Who Self-report Prolonged Abstinence From Smoking
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

This project proposes to evaluate the feasibility, acceptability, and efficacy of a mobile intervention to target smoking-cessation and increase physical activity among low-income persons. The intervention is called Smoking Treatment and Exercise Program for Underserved Populations (STEP UP).

Detailed Description

This pilot project proposes to evaluate the feasibility, acceptability, and efficacy of a mobile intervention to target smoking-cessation and physical activity among low-income persons. The intervention, named Smoking Treatment and Exercise Program for Underserved Populations (STEP UP), combines a smartphone-based contingency-management application (app), which provides monetary reinforcement for smoking abstinence and physical activity, 5 weeks of telephone-based cognitive-behavioral therapy (CBT) to prevent relapse, nicotine replacement pharmacotherapy, and text-messaging to support physical-activity goals. Participants are given a smartphone, a compact carbon-monoxide (CO) monitor, with which recency of smoking can by determined, and a Garmin Vivosmart wristband step-tracker. Twice a day at semi-random intervals, participants are prompted by the app to submit a video of themselves blowing into the CO monitor. Monetary reinforcement is then immediately provided contingent upon a below-threshold CO reading. The app also continuously syncs with the Garmin step-tracker, providing supportive messaging and bonus incentives-namely doubled reinforcement for smoking abstinence among participants who meet personalized daily step goals. The expected outcome of the project is to provide information to evaluate the efficacy of an innovative approach in preparation for a subsequent larger clinical trial that builds upon the capabilities of mHealth technology to reduce the prevalence of smoking among low income smokers.

Registry
clinicaltrials.gov
Start Date
January 2017
End Date
July 2017
Last Updated
7 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • current household income less than twice the federal poverty guidelines (Finer \& Henshaw, 2006; for instance, someone from a family of 4 must have a household income less than $48,500 to be eligible)
  • currently smoke \>10 cigarettes a day
  • smoking for at least the past year
  • can speak and write fluent conversational English
  • are 18-70 years of age
  • are willing to make an attempt to quit smoking and increase physical activity

Exclusion Criteria

  • inability to walk
  • expected to have unstable medication regimen during the study
  • currently receiving non-study behavioral treatment for smoking
  • myocardial infarction in the past 6 months
  • contraindication to nicotine replacement therapy (NRT) or bupropion with no medical clearance
  • exclusive use of other forms of nicotine such as cigars, pipes, e-cigarettes, or chewing tobacco
  • current pregnancy
  • current imprisonment or psychiatric hospitalization

Arms & Interventions

STEP UP

STEP UP is an intervention that combines evidence-based telephone cognitive behavioral counseling for smoking cessation, access to nicotine replacement therapy (NRT; including transdermal nicotine patch and either nicotine polacrilex or nicotine lozenge) and bupropion, and intensive mobile contingency management behavioral therapy administered via a smart-phone based application.

Intervention: Cognitive Behavioral Counseling

STEP UP

STEP UP is an intervention that combines evidence-based telephone cognitive behavioral counseling for smoking cessation, access to nicotine replacement therapy (NRT; including transdermal nicotine patch and either nicotine polacrilex or nicotine lozenge) and bupropion, and intensive mobile contingency management behavioral therapy administered via a smart-phone based application.

Intervention: Mobile Contingency Management

STEP UP

STEP UP is an intervention that combines evidence-based telephone cognitive behavioral counseling for smoking cessation, access to nicotine replacement therapy (NRT; including transdermal nicotine patch and either nicotine polacrilex or nicotine lozenge) and bupropion, and intensive mobile contingency management behavioral therapy administered via a smart-phone based application.

Intervention: Bupropion

STEP UP

STEP UP is an intervention that combines evidence-based telephone cognitive behavioral counseling for smoking cessation, access to nicotine replacement therapy (NRT; including transdermal nicotine patch and either nicotine polacrilex or nicotine lozenge) and bupropion, and intensive mobile contingency management behavioral therapy administered via a smart-phone based application.

Intervention: Transdermal nicotine patch

STEP UP

STEP UP is an intervention that combines evidence-based telephone cognitive behavioral counseling for smoking cessation, access to nicotine replacement therapy (NRT; including transdermal nicotine patch and either nicotine polacrilex or nicotine lozenge) and bupropion, and intensive mobile contingency management behavioral therapy administered via a smart-phone based application.

Intervention: Nicotine polacrilex

STEP UP

STEP UP is an intervention that combines evidence-based telephone cognitive behavioral counseling for smoking cessation, access to nicotine replacement therapy (NRT; including transdermal nicotine patch and either nicotine polacrilex or nicotine lozenge) and bupropion, and intensive mobile contingency management behavioral therapy administered via a smart-phone based application.

Intervention: Nicotine lozenge

Outcomes

Primary Outcomes

Number of Participants Who Self-report Prolonged Abstinence From Smoking

Time Frame: 3 month follow up

Participants will be asked to report on smoking since two weeks past quit date. Prolonged abstinence is defined as continued abstinence from smoking beginning at 2 weeks post-quit.

Number of Participants Whose Prolonged Abstinence is Bio-verified

Time Frame: 3 month follow up

Self-reported prolonged abstinence (primary outcome) will be verified by cotinine assay. Saliva samples will be collected from participants who self-report prolonged abstinence. Prolonged abstinence is defined as continued abstinence from smoking beginning at 2 weeks post-quit.

Secondary Outcomes

  • Number of Participants Who Self-report 7 Day Point Prevalence Abstinence From Smoking(6 month follow up)
  • Number of Participants Who Report 30 Day Point Prevalence Abstinence From Smoking(3 month follow up)
  • Number of Participants Who Report 7 Day Point Prevalence Abstinence From Smoking(3 month follow up)
  • Change in Physical Activity From Baseline to 3-month Follow-up as Measured by the Stanford 7-day Physical Activity Recall (PAR) Scale.(baseline and 3 month follow up)
  • Change in the Number of Days in Which Smoked Compared to Pre-quit Use(3 month follow up)
  • Change in Number of Cigarettes Smoked Per Week Compared to Pre-quit(3 month follow up)
  • Number of Quit Smoking Attempts(3 month follow up)

Study Sites (1)

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