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Virtual Reality Analgesia for Brief Thermal Pain

Not Applicable
Completed
Conditions
Pain, Acute
Interventions
Behavioral: virtual reality game
Registration Number
NCT05130307
Lead Sponsor
University of Washington
Brief Summary

Using immersive virtual reality as a form of pain distraction during a brief "painful but tolerable" temperature.

Detailed Description

This study will use Quantitative Sensory Testing (computer-controlled brief 10 second thermal pain stimuli) in healthy college students.

The primary aim is to conduct a randomized, controlled study with healthy volunteers to explore whether interacting with virtual objects in VR via a highly immersive VR system makes VR significantly more effective/powerful compared to a less immersive VR system, vs. No VR, for reducing pain during quantitative sensory testing.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
48
Inclusion Criteria
  • Currently enrolled in a course at the University of Washington Psychology Dept., participating in the UW Psychology subject pool
  • Able to read, write and comprehend English
  • Able to complete study measures
  • Willing to follow our UW approved instructions
  • 18 years of age or older
  • Currently enrolled in a course at the University of Washington Psychology Dept., participating in the UW Psychology subject pool
  • Able to read, write and comprehend English
  • Able to complete study measures
  • Willing to follow our UW approved instructions
  • 18 years of age or older The following temporary inclusion/exclusion criterion will exist only as long as required or appropriate for COVID pandemic conditions.

COVID-19 precautions. Vaccinated: Individuals are considered fully vaccinated 2 weeks after the second dose in a 2-dose series (e.g., Pfizer or Moderna) or 2 weeks after a single-dose vaccine (e.g., Johnson & Johnson).

All students and researchers must wear masks at all times during the study, and participants and researchers must provide proof of full vaccination for full participation.

If participants do not have proof of vaccination or are unvaccinated, they are still free to sign up for the study. They are invited. They can still earn the extra credit by reading educational materials, in person, during their scheduled time slot. If unvaccinated, or if they have no proof of vaccination, we request that students provide proof of a negative COVID-19 test from the UW test site at the faculty lounge, dated within 24 hours of the study (non-vaccinated students need a recent negative COVID-19 test from the UW before participating in the non-VR educational materials option.

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Exclusion Criteria
  • People how have already previously participated in this same study (e.g., last quarter) are not eligible to participate again.
  • Not enrolled in a course at the University of Washington Psychology Dept., participating in the UW Psychology subject pool
  • Not be able to read, write and comprehend English
  • Younger than 18 years of age.
  • Not capable of completing measures
  • Not capable of indicating pain intensity,
  • Not capable of filling out study measures,
  • Extreme susceptibility to motion sickness,
  • Seizure history,
  • Unusual sensitivity or lack of sensitivity to pain,
  • Sensitive skin,
  • Sensitive feet
  • Migraines
  • Diabetes

The following temporary inclusion/exclusion criterion will exist only as long as required or appropriate for COVID pandemic conditions.

COVID-19 precautions. Vaccinated: Individuals are considered fully vaccinated 2 weeks after the second dose in a 2-dose series (e.g., Pfizer or Moderna) or 2 weeks after a single-dose vaccine (e.g., Johnson & Johnson).

All students and researchers must wear masks at all times during the study, and participants and researchers must provide proof of full vaccination for full participation.

If participants do not have proof of vaccination or are unvaccinated, they are still free to sign up for the study. They are invited. They can still earn the extra credit by reading educational materials, in person, during their scheduled time slot. If unvaccinated, or if they have no proof of vaccination, we request that students provide proof of a negative COVID-19 test from the UW test site at the faculty lounge, dated within 24 hours of the study.

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Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Treatment Order 1virtual reality gameTreatment order 1: Low Tech (less interactive) Virtual Reality for 1st pain stimulus+ High Tech for 2nd pain stimulus
Treatment Order 2virtual reality gameTreatment order 2: High Tech VR (more interactive) for 1st pain stimulus + Low Tech for 2nd pain stimulus.
Primary Outcome Measures
NameTimeMethod
Worst pain, baseline, participant's rating of "worst pain" during baseline measureImmediately after a single 10 second test (no more than 10 minutes before the subsequent test stiim)

Baseline, Worst pain rating using a single graphic rating scale, 0 = no pain, 10 = excruciating pain

participant's rating of "worst pain" during test phaseImmediately after each single 10 second test stimulus (< 10 minutes after baseline pain rating)

Test phase, Worst pain rating using a single graphic rating scale, 0 = no pain, 10 = excruciating pain

Secondary Outcome Measures
NameTimeMethod
Baseline, participants rating of "Fun" during baselineImmediately after a single 10 second test (no more than 10 minutes before the subsequent test stiim)

Baseline fun, 0 = no fun at all, 10 = extremely fun

Baseline pain intensity: participants ratings of pain intensity during brief pair of 10 sec stimuliImmediately after a single 10 second test (no more than 10 minutes before the subsequent test stiim)

Baseline, pain intensity rating using a single graphic rating scale, 0 = no pain, 10 = excruciating pain

Baseline, participants rating of "time spent thinking about pain"Immediately after a single 10 second test (no more than 10 minutes before the subsequent test stiim)

Baseline Time thinking, Single a single graphic rating scale, 0 = none of the time, 10 = all of the time

Test phase, participants rating of "pain unpleasantness" during test phaseImmediately after each single 10 second test stimulus (< 10 minutes after baseline pain rating)

Test phase, pain unpleasantness, 0 = not unpleasant at all, 10 = excruciatingly unpleasant

Test Phase, participants rating of "time spent thinking about pain" during test phaseImmediately after each single 10 second test stimulus (< 10 minutes after baseline pain rating)

Test phase, Time rating, using a single graphic rating scale, 0 = none of the time, 10 = all of the time

Test Phase, participants ratings of "Fun" during test phaseImmediately after each single 10 second test stimulus (< 10 minutes after baseline fun rating)

Test phase fun, 0 = no fun at all, 10 = extremely fun

Baseline, participants rating of "pain unpleasantness"Immediately after a single 10 second test (no more than 10 minutes before the subsequent test stiim)

Baseline, Unpleasant rating, using single graphic rating scale, 0 = not unpleasant at all, 10 = excruciatingly unpleasant

Accuracy on the odd number task during No VR, Low tech VR and High tech VRNo pain during this measure, measured within 10 minutes after the QST measures are completed.

participants accuracy on the attention demanding "odd number" task (Hoffman, 2021)

Trial Locations

Locations (1)

University of Washington (only Psych students eligible, public not eligible for participation)

🇺🇸

Seattle, Washington, United States

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