A study to evaluate the lung function by using sonography in very sick children admitted in IC
Not Applicable
- Conditions
- Health Condition 1: C81-C96- Malignant neoplasms of lymphoid, hematopoietic and related tissue
- Registration Number
- CTRI/2023/11/059523
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Children <16 year admitted to ICU
2. On a fixed Fio2 device (Invasive mechanical ventilation (IMV)/ High-flow nasal cannula (HFNC)/ Non-invasive ventilation (NIV)) or room air
3. Neutropenia at the time of enrollment. absolute neutrophil count (ANC) <500 cells/ µL
4. Need of arterial blood
Exclusion Criteria
1. Refusal of consent to participate
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the correlation between lung ultrasound score (LUSS) and P/F ratio (ratio of arterial oxygen partial pressure (PaO2 in mmHg) to fractional inspired oxygen (FiO2))Timepoint: At the time of admission, <br/ ><br>At 3rd day, <br/ ><br>At 6th day, <br/ ><br>and within 24 hrs of CT Thorax imaging
- Secondary Outcome Measures
Name Time Method A.Association of admission LUSS score and clinical indices - ventilator free days, ICU and hospital mortalityTimepoint: At the time of admission, <br/ ><br>At 3rd day, <br/ ><br>At 6th day, <br/ ><br>and within 24 hrs of CT Thorax imaging;B.Correlation between Lung ultrasound score (LUSS) and SpO2/Fio2 ratio and Oxygenation indexTimepoint: At the time of admission, <br/ ><br>At 3rd day, <br/ ><br>At 6th day, <br/ ><br>and within 24 hrs of CT Thorax imaging;C.Correlation between S/F ratio and P/F ratio (ratio of oxygen saturation (SpO2) to fractional inspired oxygen (FiO2)Timepoint: At the time of admission, <br/ ><br>At 3rd day, <br/ ><br>At 6th day, <br/ ><br>and within 24 hrs of CT Thorax imaging