MedPath

Pregabalin In Adolescent Patients With Fibromyalgia

Phase 4
Completed
Conditions
Fibromyalgia
Interventions
Registration Number
NCT01020526
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Brief Summary

The main purpose of this study is to evaluate the long-term safety of pregabalin in adolescent patients who participated in the previous fibromyalgia study (A0081180) and who wish to recieve open-label pregabalin

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
63
Inclusion Criteria
  • Patients must have met the inclusion criteria for the preceding fibromyalgia Study A0081180, and have received pregabalin/placebo under double-blind conditions.
Exclusion Criteria
  • Patients may not participate in the study if they experienced a serious adverse event during the previous fibromyalgia study A0081180 which was determined to be related to the study medication by the investigator or sponsor.

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Pregabalinpregabalin-
Primary Outcome Measures
NameTimeMethod
Change From Baseline in Pain Numeric Rating Scale by WeekBaseline, Weeks 3, 8, 16, 24 and Last Visit.

The weekly pain numeric rating scale (Weekly Pain NRS) consists of an 11-point NRS ranging from 0 (no pain) to 10 (worst possible pain), where higher scores indicate worse pain. Participants chose the number that best described the pain during the last week. Negative change indicates improvement.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (25)

Sushrut Hospital, Research Centre & Post Graduate Institute of Orthopaedics

🇮🇳

Nagpur, Maharashtra, India

University of Louisville

🇺🇸

Louisville, Kentucky, United States

Krishna Institute of Medical Sciences Ltd

🇮🇳

Secunderabad, Andhra Pradesh, India

Mallikatta Neuro Center

🇮🇳

Mangalore, Karnataka, India

Nationwide Children's Hospital

🇺🇸

Columbus, Ohio, United States

Rheumatology Associates of Central Florida, PA

🇺🇸

Orlando, Florida, United States

Childrens Hospital Los Angeles

🇺🇸

Los Angeles, California, United States

University of Massachusetts Memorial Medical Center Department of Pediatrics

🇺🇸

Worcester, Massachusetts, United States

The Research Institute at Nationwide Children's Hospital

🇺🇸

Columbus, Ohio, United States

Bioregeneracni a rehabilitacni centrum

🇨🇿

Ricany, Czechia

King George's Medical University

🇮🇳

Lucknow, Uttar Pradesh, India

University of Cincinnati Department of Psychiatry and Behavioral Neuroscience

🇺🇸

Cincinnati, Ohio, United States

Apex Research Institute

🇺🇸

Santa Ana, California, United States

Florida Medical Center & Research

🇺🇸

Miami, Florida, United States

Medical Research & Health Education Foundation, Inc.

🇺🇸

Columbus, Georgia, United States

Harmony Clinical Research, Incorporated

🇺🇸

North Miami Beach, Florida, United States

Kosair Charities Pediatric Clinical Research Unit

🇺🇸

Louisville, Kentucky, United States

University Pediatric Rheumatology of Kentucky, LLC

🇺🇸

Louisville, Kentucky, United States

Akron Children's Hospital

🇺🇸

Boardman, Ohio, United States

Akron Children's Hospital-Mahoning Valley

🇺🇸

Boardman, Ohio, United States

Medical University of South Carolina

🇺🇸

Charleston, South Carolina, United States

Medical University of South Carolina, Pediatric Rheumatology

🇺🇸

Charleston, South Carolina, United States

Kosair Children's Hospital

🇺🇸

Louisville, Kentucky, United States

Carolina Research Center

🇺🇸

Myrtle Beach, South Carolina, United States

Fatigue Consultation Clinic

🇺🇸

Salt Lake City, Utah, United States

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