Effect of fluoride and xylitol varnish on oral microorganism
Phase 3
Recruiting
- Conditions
- Cariogenic bacteria in the oral cavity.
- Registration Number
- IRCT20181121041713N4
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Age between 12 and 30 years old
Permanent dentition
Good general health
No anti-inflammatory or antibiotic medications taken in the month before the study
No chewing gum or mouthwash use in the last week and during the study
Brushing twice daily with fluoride toothpaste
No active or untreated caries lesions or gingival inflammation
Exclusion Criteria
Treatment with antibiotics, steroids or any medication known to cause dry mouth in the last 3 months
Poor oral hygiene
Active periodontal disease
Sever crowding of anterior teeth that would be likely to interfere with cleaning of tooth surface
Smoking
History of mouth breathing
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of bacterial colonies. Timepoint: Before beginning the intervention and 45 days later. Method of measurement: Counting the number of bacterial colonies.
- Secondary Outcome Measures
Name Time Method . Timepoint: . Method of measurement: .