The Effect of Xylitol and Saline Nasal Irrigations on the Sinus Microbiome in Patients with Chronic Rhinosinusitis

Not Applicable

Recruiting

• Conditions: Chronic Sinusitis; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12615000154505
• Lead Sponsor: Associate Professor Richard Douglas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-02-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients diagnosed with chronic rhinosinusitis
Patients providing full-informed consent to participate in this study

Exclusion Criteria

1. Children (<16 years)
2. Cystic fibrosis
3. Immunodeficiency (congenital or acquired)
4. Congenital mucociliary problems (e.g. primary ciliary dyskinesia)
5. Non-invasive and invasive fungal sinus disease
6. Systemic vasculitis and granulomatous diseases
7. History of cocaine abuse;
8. Patients requiring sinus surgery for neoplasia
9. Patients unable to consent (e.g. lack of mental capacity)

Study & Design

• Study Type: Interventional
• Study Design: Not specified