Effect of Xylitol nasal spray in treatment of chronic rhinosinusitis

Phase 2

• Conditions: Rhinosinusitis.; Chronic sinusitis, unspecified; J32.9

• Registration Number: IRCT20171030037093N35
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 18 May 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients with chronic rhinosinusitis
Age over 18 years
They had previously undergone sinus endoscopy and now need only non-surgical treatments.

Exclusion Criteria

Patients who have a history of allergic rhinitis, asthma, immunodeficiency, cystic fibrosis, primary pulmonary dyskinesia, active bacterial or fungal infection and need antibiotics or antifungals
Patients who are unsatisfied with non-surgical treatment or want to have surgery again for any reason
Have a history of head and neck radiation therapy
Now be a smoker
Pregnant people
Have granulomatous disease

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
und Kennedy Score. Timepoint: Before and after the study. Method of measurement: Lund Kennedy questionnaire.;SNOT 22 (Sino-nasal Outcome Test) score. Timepoint: Before the intervention and 30 days after the intervention. Method of measurement: SNOT 22 (Sino-nasal Outcome Test).;Severe pain when pressing on the sinuses. Timepoint: Before and after the study. Method of measurement: VAS (Visual Analog Scale) questionnaire.