Treatment of hospital-acquired pneumonia with multi-drug resistant organism by Buzhong Yiqi Decoction based on the Fuzheng Quxie Classical Prescription: a multicenter, randomized, controlled clinical trial
- Conditions
- Hospital-acquired pneumonia with multi-drug resistant organism
- Registration Number
- ITMCTR1900002274
- Lead Sponsor
- ongHua Hospital Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Complying with the diagnostic criteria of Western Medicine;
(2) Pathogenic diagnosis conforms to MDRO criteria;
(3) Aged 40-85 years;
(4) Signing informed consent.
(1) Having serious heart, brain, liver, kidney and other primary diseases or malignant tumors, systemic diseases and other diseases in the acute or progressive stage;
(2) with a history of operation within two months, accompanied by infection of the surgical site;
(3) Death within 72 hours after admission;
(4) Psychiatric patients and pregnant women;
(5) active pulmonary tuberculosis;
(6) those who have a history of allergy to medicines in treatment;
(7) Recent drug and alcohol abuse;
(8) Those who failed to respond to other antibiotics or other drugs three months before the drug clinical trial.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inflammatory factor level;clinical pulmonary infection score;Removal rate of drug-resistant pathogens;
- Secondary Outcome Measures
Name Time Method Integral of TCM Syndrome;Assessment of severity of illness;Hospitalization Days;mortality rate;successful rate of weaning from mechanical ventilation;Mechanical ventilation time;Pulmonary CT Imaging;