Is it better to treat pneumonia by customising antibiotic treatment based on the PIBCAP test compared to the current standard NHS treatment?
Not Applicable
- Conditions
- Community-acquired pneumoniaRespiratoryPneumonia, organism unspecified
- Registration Number
- ISRCTN42850134
- Lead Sponsor
- HS Lothian
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Stopped
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
1. Hospitalised for CAP
2. Uncomplicated CAP confirmed by physician
3. CURB65 score two or more
4. Aged 16 and over
Exclusion Criteria
1. Immunodeficiency - defined as being on long term (?28 days) oral prednisolone 10mg or more per day or other long-term disease-modifying drug
2. All forms of pulmonary fibrosis including usual interstitial pneumonia, asbestosis, non-specific interstitial pneumonia, hypersensitivity pneumonitis, active sarcoidosis
3. No capacity to consent
4. Active malignancy
5. Solid organ transplant
6. COPD on domiciliary oxygen therapy
7. Palliative treatment only
8. Mechanical ventilation
9. End of life care
10. Previously randomised into this trial
11. Participation in another CTIMP or CIMD interventional study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical outcome measured with Desirability of Outcome Ranking (DOOR) and then further ranked using the Response Adjusted for Duration of Antibiotic Risk, assessed at day 30
- Secondary Outcome Measures
Name Time Method