Efficacy of Fractional Carbon Dioxide Laser versus Autologous Platelet Rich Plasma versus Microneedling with topical Aloe Vera Gel in the Treatment of Striae Distensae
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- 1. Measurement of efficacy of modalities on the basis of quartile grading score.
研究概览
简要总结
This study is to Determine the efficacy of Fractional CO2 Laser versus PRP versus Microneedling with Aloe Vera Gel in the treatment of Striae Distensae. As of now, no study has been done to compare these three groups. Thus making this study a first of its kind.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of both genders with striae Distensae of all grades over any site on the body
- •Patients who have not taken treatment for striae distensae either topppical or systemic in the past 6 months.
排除标准
- •1.Patients on systemic isotretinoin or corticosteroids.
- •2.Patients with history of keloid formation.
- •3.Patients with any connective tissue disease.
- •4.Patients with disease affecting the wound-healing process.
- •5.Patients with other systemic illness – cardiac, renal, hepatic illness.
- •6.Severely Immunocompromised 7.Pregnancy, Lactation 8.Patients who have cold intolerance 9.Patients taking photosensitive drugs and photosensitivity 10.Patient not willing for study.
结局指标
主要结局
1. Measurement of efficacy of modalities on the basis of quartile grading score.
时间窗: 1. before each setting - every 3 weeks | 2, 3 - at end of 6 settings and 3 weeks after the last setting - at 15 weeks
3. Patient satisfaction using Likert Satisfaction scale
时间窗: 1. before each setting - every 3 weeks | 2, 3 - at end of 6 settings and 3 weeks after the last setting - at 15 weeks
2. % reduction in width of Striae
时间窗: 1. before each setting - every 3 weeks | 2, 3 - at end of 6 settings and 3 weeks after the last setting - at 15 weeks
次要结局
- Post procedural adverse effects & healing effects of Fractional Carbon Dioxide Laser, PRP, and Microneedling with topical aloe vera gel in treatment of striae distensae.(1. before each setting - every 3 weeks, at end of 6 settings)