Effectiveness of Intratympanic Dexamethasone With Ligmocaine for Alleviation of Tinnitus

Phase 4

• Conditions: Tinnitus
• Interventions: Drug: Dexamethasone

• Registration Number: NCT04798391
• Lead Sponsor: Combined Military Hospital, Pakistan

Brief Summary

Objective: To determine the effectiveness of Intratympanic dexamethasone with lignocaine in control of idiopathic tinnitus.

Methodology: 264 consenting patients with idiopathic unilateral tinnitus presenting at ENT Department were assessed for tinnitus severity using Modified Tinnitus Handicap Inventory and the scores recorded and subsequently administered intratympanically 2.0 ml (milliliter's) of dexamethasone and lignocaine (1.5 ml dexamethasone + 0.5 ml 1% lignocaine). The dose was repeated twice at weekly intervals. All patients were re assessed on Modified Tinnitus Handicap Inventory two weeks after third Intratympanic administration.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2021-03
• Study Start: 2021-03-01
• Study First Submitted: 2021-03-06
• Study First Submitted QC: 2021-03-12
• Last Update Submitted: 2021-03-12
• Study First Posted: 2021-03-15
• Last Update Posted: 2021-03-15
• Primary Completion: 2021-04
• Study Completion: 2021-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 264

Inclusion Criteria

• score 20 or above on modified tinnitus handicap inventory

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Exclusion Criteria

• head trauma, tympanic membrane perforation, depression, ear surgery

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Dexamethasone with lignocaine	Dexamethasone	-

Primary Outcome Measures

Name	Time	Method
Tinnitus relief	2 weeks	Tinnitus relief ascertained by Modified Tinnitus Handicap Inventory

Trial Locations

Locations (1)

Combined Military Hospital; 🇵🇰 Quetta, Balochistan, Pakistan