Respiratory muscle strength in pulmonary fibrosis

• Conditions: J84.1; Other interstitial pulmonary diseases with fibrosis

• Registration Number: DRKS00000817
• Lead Sponsor: niversitätsklinik FreiburgAbt. Pneumologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2011-04-14
• Study Start: 2011-05-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 49

Inclusion Criteria

histologically assessed pulmonary fibrosis in the patient group

Exclusion Criteria

Patients:
other lung diseases
right heart failure
diabetes mellitus
neuromuscular diseases

Control subjects
Lung diseases
severe cardiac disease
diabetes mellitus
neuromuscular diseases

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
One-time assessment of twitch mouth pressure after bilateral anterior magnetic stimulation as a measure of diaphragmatic strength using an automated shutter-occluded spirometer.

Secondary Outcome Measures

Name	Time	Method
One-time assessment of global respiratory muscle strength (PImax), respiratory drive (P0.1) and Sniff pressure at the mouth using an automated shutter-occluded spirometer. Correlation of respiatroy muscle strength with performance in the 6min walking test and diseas-specific laboratoy parameters (CCL18).