Study on Variables Able to Predict Fluid Responsiveness Using Lung Recruitment Maneuver in Pediatric Patients Undergoing General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- photoplethysmographic waveform
研究概览
简要总结
Lung recruitment maneuver induces a decrease in stroke volume, which is more pronounced in hypovolemic patients. The authors hypothesized that the changes of dynamic variables through lung recruitment maneuver could predict preload responsiveness in pediatric patients with lung protective ventilation
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- — 至 6 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •pediatric patients undergoing general anesthesia under 6 years old
排除标准
- •arrhythmia
- •<30%, ejection fraction
- •lung disease
研究组 & 干预措施
lung recruitment maneuver
Heart rate, mean arterial pressure, stroke volume, pulse pressure variations, pleth variability index, and photoplethysmographic waveform were recorded before lung recruitment maneuver (application of continuous positive airway pressure of 25 cm H2O for 20 s), during lung recruitment maneuver when stroke volume reached its minimal value.
Cardiac index measured before and after volume expansion (10ml/kg saline, 0.9%, infused during 10 min). Patients were considered as responders to fluid administration if cardiac index increased greater than or equal to 15%.
干预措施: lung recruitment maneuver (Diagnostic Test)
结局指标
主要结局
photoplethysmographic waveform
时间窗: change from baseline photoplethysmographic waveform after lung recruitment maneuver within 30 seconds
次要结局
未报告次要终点
研究者
Jin-Tae Kim
professor
Seoul National University Hospital