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Clinical Trials/NCT03843411
NCT03843411
Withdrawn
Not Applicable

Mini-fluid Challenge as a Predictor of Fluid Response for Pneumoperitoneum Patient

Changhua Christian Hospital0 sitesOctober 2019
ConditionsAnesthesia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Anesthesia
Sponsor
Changhua Christian Hospital
Primary Endpoint
change of stroke volume index
Status
Withdrawn
Last Updated
6 years ago

Overview

Brief Summary

The purpose of this study is to evaluate whether the change of stroke volume index(△SVI) induced by the rapid mini-fluid administration can predict fluid responsiveness in patients with pneumoperitoneum

Detailed Description

Perioperative fluid management is significant important during surgery. The current trend tends to use goal-directed fluid therapy in surgery. Goal-directed fluid therapy refers to continuous monitoring of hemodynamic parameters during surgery and managing more accurate fluid administration based on the data obtained while promoting optimal tissue perfusion. Define fluid responsiveness with the hemodynamic parameters as to whether the cardiac output can be significantly increased after administration of fluid. Therefore, the advantage of predicting fluid responsiveness is that it can optimize the cardiac output and tissue perfusion while avoiding administering unnecessary fluid to patients. The purpose of this study is to evaluate whether the change of stroke volume index(△SVI) induced by the rapid mini-fluid administration can predict fluid responsiveness in patients with pneumoperitoneum.

Registry
clinicaltrials.gov
Start Date
October 2019
End Date
October 2020
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • receive operation that required pneumoperitoneum and FloTrac monitoring
  • age between 20 to 70 year old

Exclusion Criteria

  • patient who cannot understand the process and aim of the study
  • patient with arrhythmia
  • poor heart function(LVEF\<50%, severe valvular disease, CAD)
  • pregnant patient
  • patients allergic to voluven

Outcomes

Primary Outcomes

change of stroke volume index

Time Frame: 1 hours

record stroke volume index before and after mini-fluid challenge

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