Prediction of Fluid Responsiveness From Passive Leg Raising Induced Changes in Perfusion Index and Pleth Variability Index
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Fluid Responsiveness
- Sponsor
- Institute of Mountain Emergency Medicine
- Enrollment
- 51
- Locations
- 1
- Primary Endpoint
- PI difference
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The aim of the study is to evaluate whether changes in Perfusion Index (PI) and Pleth Variability Index (PVI) during passive leg raising test can predict fluid responsiveness in spontaneously breathing patients.
Fluid responsive patients are defined as showing an increase in cardiac output >10% during a passive leg raising test, measured semi-invaseively with FloTrac® (Edwards LifeSciences. Irvine, United States).
Investigators
Simon Rauch
Researcher
Institute of Mountain Emergency Medicine
Eligibility Criteria
Inclusion Criteria
- •Adult patients admitted to the intensive or intermediate care unit after abdominal surgery (including urological and gynecological surgery performed in laparotomy)
- •Spontaneous breathing
- •Arterial line already in place
- •Oral and written informed consent obtained
Exclusion Criteria
- •Age \<18 years
- •Abdominal trauma as the reason for surgery
- •Missing informed consent
Outcomes
Primary Outcomes
PI difference
Time Frame: 90 seconds
Difference in the change of perfusion index from baseline during a passive leg raising maneuver in fluid responsive patients compared to fluid non-responders
PVI difference
Time Frame: 90 seconds
Difference in the change of pleth variability index from baseline during a passive leg raising maneuver in fluid responsive patients compared to fluid non-responders