Interest of the Pleth Variability Index in Neurosurgery
- Conditions
- Intraoperative MonitoringHypovolemiaFluid Challenge
- Registration Number
- NCT06624891
- Lead Sponsor
- National Institute of Neurology, Tunisia
- Brief Summary
This clinical trial aims to study the interest of the Pleth Variability Index (PVI) to evaluate perioperative fluid responsiveness in neurosurgery in adults.
The main question it aims to answer is:
• Does the Pleth variability index predict fluid responsiveness in neurosurgery? Researchers will compare the Pleth variability index to dela PP to see if it predicts fluid responsiveness in neurosurgery.
Once participants give their consent, they will be randomly assigned to one of two groups. In one group, fluid responsiveness will be monitored using the Pleth Variability Index, while in the other group, it will be monitored using delta PP.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 70
- Patients proposed for intracranial surgery
- Must be aged 18 and over
- Must be classified as ASA I, ASA II, and ASA III according to the American Society of Anesthesiologists classification
- Non-consenting patients
- Patients classified ASA IV or higher
- Cardiac arrhythmia
- Heart disease with left ventricular ejection fraction less than 45%
- Obesity with a BMI greater than 40 Kg/m2.
- Peripheral vascular disease
- Severe lung disease
- End-stage renal disease
- Intraoperative cardiac arrhythmia
- The occurrence of cardiac arrest
- The occurrence of hemorrhagic shock
- Intraoperative use of low tidal volumes or high respiratory rates.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Value of PVI in fluid responsiveness in neurosurgery chanfe of PVI value from baseline to a value more than 14% and untill the end of surgery Investigate the value of the plethysmographic variability index (PVI) in assessing the response to perioperative vascular filling in neurosurgery.
- Secondary Outcome Measures
Name Time Method Amount of fluids administered intraoperatively during the surgery Renal, metabolic and hydroelectrolytic repercussions. up to the first 24 hours postoperatively Length of postoperative stay up to hospital discharge, an average of 4 days Incidence of post-operative complications up to hospital discharge, an average of 4 days
Trial Locations
- Locations (1)
National Institute of Neurologie Mongi Ben-Hamida
🇹🇳Tunis, Tunisia
National Institute of Neurologie Mongi Ben-Hamida🇹🇳Tunis, Tunisia