The Application of Pleth Variability Index in Continuous Monitoring Volume Status in Patients Undergoing Intestinal Tumor Surgery
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 主要终点
- the correlation of SVV and PVI
研究概览
简要总结
To assess the value of using pleth variability index(PVI) to monitor the patient's intra-operative volume status continuously by observing the application of stroke volume variation(SVV) and PVI and their correlation in patients undergoing intestinal tumor surgeries.
详细描述
Objective
To assess the value of using PVI to monitor the patient's intra-operative volume status continuously by observing the application of stroke volume variation(SVV) and pleth variability index(PVI) and their correlation in patients undergoing intestinal tumor surgeries.
Methods: 50 patients undergoing elective intestinal tumor surgery were enrolled, ASAⅠ-Ⅲ, aged 18-65 years. After the induction of general anesthesia, cardiac index(CI), cardiac output(CO), stroke volume variability(SVV), stroke volume index(SVI) were monitored with Vigileo system, while pleth variability index(PVI) and perfusion index(PI) were monitored with Massion Radical 7 system. During the surgery, goal directed fluid therapy was conducted according to the data of CI、SVI and SVV. Heart rate(HR), mean arterial pressure(MAP), central venous pressure(CVP), CO, CI, SVI, SVV, PI, PVI were recorded while after the induction of anesthesia(T1), making surgical incision(T2), performing intestinal anastomosis(T3) and closing the abdominal incision(T4). And we calculate the correlation of SVV and PVI using Pearson Correlation Analysis at different time points.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing elective intestinal tumor surgery
- •American Society of Anesthesiologists (ASA) physical status of grade I-Ⅲ
- •Aged 18-65 years
- •BMI 18~30kg/㎡
排除标准
- •Patients under 18 years or above 65 years
- •patients with severe aortic regurgitation
- •patients with permanent cardiac arrhythmias
- •patients with intra-aortic balloon pump
- •patients with severe pulmonary disease
- •patients undergoing emergency surgery
结局指标
主要结局
the correlation of SVV and PVI
时间窗: during the surgery
SVV and PVI were recorded while after the induction of anesthesia(T1),making surgical incision(T2),performing intestinal anastomosis(T3) and closing the abdominal incision(T4). We calculate the correlation of SVV and PVI using Pearson Correlation Analysis at different time points.
次要结局
- pleth index(PI)(during the surgery)
- cardiac index(CI)(during the surgery)
- stroke volume index(SVI)(during the surgery)
- stroke volume variability(SVV)(during the surgery)
- pleth variability index(PVI)(during the surgery)
研究者
Lin Yang
attending physician
First Affiliated Hospital, Sun Yat-Sen University