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Clinical Trials/NCT03009669
NCT03009669
Unknown
Not Applicable

The Application of Pleth Variability Index in Continuous Monitoring Volume Status in Patients Undergoing Intestinal Tumor Surgery

First Affiliated Hospital, Sun Yat-Sen University0 sites50 target enrollmentDecember 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hemodynamic Monitoring
Sponsor
First Affiliated Hospital, Sun Yat-Sen University
Enrollment
50
Primary Endpoint
the correlation of SVV and PVI
Last Updated
9 years ago

Overview

Brief Summary

To assess the value of using pleth variability index(PVI) to monitor the patient's intra-operative volume status continuously by observing the application of stroke volume variation(SVV) and PVI and their correlation in patients undergoing intestinal tumor surgeries.

Detailed Description

Objective: To assess the value of using PVI to monitor the patient's intra-operative volume status continuously by observing the application of stroke volume variation(SVV) and pleth variability index(PVI) and their correlation in patients undergoing intestinal tumor surgeries. Methods: 50 patients undergoing elective intestinal tumor surgery were enrolled, ASAⅠ-Ⅲ, aged 18-65 years. After the induction of general anesthesia, cardiac index(CI), cardiac output(CO), stroke volume variability(SVV), stroke volume index(SVI) were monitored with Vigileo system, while pleth variability index(PVI) and perfusion index(PI) were monitored with Massion Radical 7 system. During the surgery, goal directed fluid therapy was conducted according to the data of CI、SVI and SVV. Heart rate(HR), mean arterial pressure(MAP), central venous pressure(CVP), CO, CI, SVI, SVV, PI, PVI were recorded while after the induction of anesthesia(T1), making surgical incision(T2), performing intestinal anastomosis(T3) and closing the abdominal incision(T4). And we calculate the correlation of SVV and PVI using Pearson Correlation Analysis at different time points.

Registry
clinicaltrials.gov
Start Date
December 2016
End Date
September 2017
Last Updated
9 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
First Affiliated Hospital, Sun Yat-Sen University
Responsible Party
Principal Investigator
Principal Investigator

Lin Yang

attending physician

First Affiliated Hospital, Sun Yat-Sen University

Eligibility Criteria

Inclusion Criteria

  • patients undergoing elective intestinal tumor surgery
  • American Society of Anesthesiologists (ASA) physical status of grade I-Ⅲ
  • Aged 18-65 years
  • BMI 18\~30kg/㎡

Exclusion Criteria

  • Patients under 18 years or above 65 years
  • patients with severe aortic regurgitation
  • patients with permanent cardiac arrhythmias
  • patients with intra-aortic balloon pump
  • patients with severe pulmonary disease
  • patients undergoing emergency surgery

Outcomes

Primary Outcomes

the correlation of SVV and PVI

Time Frame: during the surgery

SVV and PVI were recorded while after the induction of anesthesia(T1),making surgical incision(T2),performing intestinal anastomosis(T3) and closing the abdominal incision(T4). We calculate the correlation of SVV and PVI using Pearson Correlation Analysis at different time points.

Secondary Outcomes

  • pleth index(PI)(during the surgery)
  • cardiac index(CI)(during the surgery)
  • stroke volume index(SVI)(during the surgery)
  • stroke volume variability(SVV)(during the surgery)
  • pleth variability index(PVI)(during the surgery)

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