Pleth Variability Index (PVI) to Predict Fluid Responsiveness
Not Applicable
Withdrawn
- Conditions
- Anesthesia
- Registration Number
- NCT03120910
- Lead Sponsor
- Masimo Corporation
- Brief Summary
Interventional data collection study to evaluate the ability of pleth variability index (PVI) to predict fluid responsiveness in comparison with other dynamic parameters including pulse pressure variation (PPV) and stroke volume variation (SVV).
- Detailed Description
No subjects were enrolled into the validation portion of this study.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- 18 years of age or older
- Scheduled for elective surgery requiring general anesthesia and mechanical ventilation
- Arterial line and Swan-Ganz catheter placement indicated as part of the scheduled surgical procedure
Exclusion Criteria
- Patients with surgeries at or around site of sensor placement or skin abnormalities affecting the sensor placement area such as psoriasis, eczema, angioma, scar tissue, burn, fungal infection, substantial skin breakdown, nail polish, or acrylic nails that would prevent monitoring of pulse-oximeter physiological parameters during the study
- Patients with cardiac arrhythmias
- Patients with intracardiac shunts
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Clinical utility of PVI 1-5 hours Correlation between PVI and SVV to assess PVI as a predictor for fluid responsiveness.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the physiological mechanisms linking PVI to fluid responsiveness in anesthetized patients?
How does PVI's predictive accuracy compare to PPV and SVV in dynamic hemodynamic monitoring during anesthesia?
Which biomarkers correlate with PVI's reliability in predicting fluid responsiveness under general anesthesia?
What adverse events are associated with Masimo's Pulse CO-Oximeter Sensor during PVI-guided fluid management?
Are there alternative hemodynamic monitoring devices or parameters to PVI for assessing fluid responsiveness in surgical settings?
Trial Locations
- Locations (1)
UC Davis
🇺🇸Sacramento, California, United States
UC Davis🇺🇸Sacramento, California, United States