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Clinical Trials/NCT04002193
NCT04002193
Completed
Not Applicable

Pleth Variability Index as Predictors of Fluid Responsiveness in Modified Prone Position(Concord Position) or Knee-chest Position

Asan Medical Center1 site in 1 country44 target enrollmentDecember 6, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fluid Responsiveness
Sponsor
Asan Medical Center
Enrollment
44
Locations
1
Primary Endpoint
To assess influence of the position change on PVI and other variables(PPV, SVV)
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

To investigate whether PVI predicts the fluid responsiveness in modified prone position undergoing posterior approach cervical operation. Furthermore, modified prone position could influence on dynamic variables including stroke volume variation(SVV), pulse pressure variation(PPV) and PVI.

Detailed Description

Objective : To compare measurements of pleth variability index (PVI), pulse pressure variation (PPV) and stroke volume variation (SVV) to predict fluid responsiveness in modified prone position or knee-chest position (concord position) for cervical operation. To identify Influence of the modified prone position (concord position) on these variables. Method 1. To assess influence of the position change on PVI and other variables(PPV, SVV) 2. To assess PVI to predict fluid responsiveness at modified prone position

Registry
clinicaltrials.gov
Start Date
December 6, 2019
End Date
October 31, 2020
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Heesun Park

Clinical instructor of Anesthesiology and Pain department

Asan Medical Center

Eligibility Criteria

Inclusion Criteria

  • American Society of Anaesthesiologists'(ASA) physical status 1-3
  • patients who received cervical operation in modified prone position or knee-chest position

Exclusion Criteria

  • Valvular heart disease
  • Congestive heart failure, reduced left ventricular function ( Ejection fraction \< 40%)
  • Moderate grade of pulmonary disease
  • Arrhythmia (atrial fibrillation, atrial flutter.. etc.)
  • body mass index \> 30 or \< 15 kg/m2

Outcomes

Primary Outcomes

To assess influence of the position change on PVI and other variables(PPV, SVV)

Time Frame: 1.supine position : 5 minute after anesthesia induction with arterial-line insertion 2. 5 min after crystalloid 4 ml/kg loading / 3. modified prone position (baseline)

When position change from supine to modified prone position, to assess the change of PVI and other variables. The correlation of PVI and cardiac output during this change.

Secondary Outcomes

  • To measure dynamic variables (pulse pressure variation, stroke volume variation and pleth variability index) in modified prone position(1. Supine position : 5 minute after anesthesia induction with arterial-line insertion 2. 5 minute after a position change to prone 3. before and after fluid loading)

Study Sites (1)

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