Accuracy of Pleth Variability Index (PVI) in Predicting Response to Intravenous Fluid Load During Scoliosis Surgery in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Plethysmographic Variability before each fluid challenge and percentage of variation in Indexed Stroke Volume during each fluid challenge.
研究概览
简要总结
Plethysmographic Variability index is a simple index accurate in predicting fluid responsiveness.
The aim of this study was to investigate its accuracy in predicting fluid response to intravenous fluid challenge during scoliosis surgery in children.
详细描述
The goal of the present study is to assess the validity of PVI in predicting the response to a fluid challenge during scoliosis surgery in children.
During this observational non-interventional study, each fluid challenge will be monitored by esophageal Doppler and PVI (Massimo Radical 5).
Anesthesia, surgery and intraoperative fluid administration id standardized according to our clinical protocol.
An increase in indexed Stroke Volume (iSV) by more than 15 % will define the positive response to the fluid challenge.
Fluid challenges will be performed in the supine position and in the prone position.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 2 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Scoliosis surgery
- •Age < 18 years
排除标准
- •Heart or vascular Diseases
- •Rectal abnormalities
- •Kidney Failure
- •Neuromuscular scoliosis
结局指标
主要结局
Plethysmographic Variability before each fluid challenge and percentage of variation in Indexed Stroke Volume during each fluid challenge.
时间窗: During the intraoperative period.
Data will be used to assess the accuracy of Plethysmographic Variability Index in predicting fluid challenge.
次要结局
- Indexed Stroke volume before each fluid challenge and percentage of variation in indexed Stroke volume during each fluid challenge.(During the intraoperative period)