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临床试验/NCT06734650
NCT06734650
尚未招募
不适用

Development and Validation of a Peripheral Venous Waveform-based Pulse Pressure Variation Calculating Deep Learning Model

Seoul National University Bundang Hospital1 个研究点 分布在 1 个国家目标入组 150 人2024年12月28日

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Peripheral Vein
发起方
Seoul National University Bundang Hospital
入组人数
150
试验地点
1
主要终点
Pulse pressure variation
状态
尚未招募
最后更新
去年

概览

简要总结

Pulse pressure variation is a monitoring index that indicates the response to fluid therapy in patients receiving mechanical ventilation, and is used as a reference for patients with unstable hemodynamic conditions. However, it is invasive because it requires arterial puncture to collect it. In a previous study by the investigators, the investigators developed and verified an artificial intelligence model that predicts stroke volume variation, in real time using only the central venous pressure waveform. However, since a large vein such as the jugular vein must be punctured to collect the central venous pressure waveform, it is still invasive, and its clinical utility is low. Therefore, in this study, the investigators collected waveforms from peripheral veins that are less invasive and can be a wide range of applications because all surgical patients have them. The investigators aimed to develop and verify an artificial intelligence model that predicts pulse pressure variation obtained from peripheral venous waveforms .

详细描述

In this study, the investigators collected waveforms from peripheral veins that are less invasive and can be a wide range of applications because all surgical patients have them. The investigators aimed to develop and verify an artificial intelligence model that predicts pulse pressure variation obtained from peripheral venous waveforms .

注册库
clinicaltrials.gov
开始日期
2024年12月28日
结束日期
2026年11月28日
最后更新
去年
研究类型
Observational
性别
All

研究者

责任方
Principal Investigator
主要研究者

Park InSun

Principal investigator

Seoul National University Bundang Hospital

入排标准

入选标准

  • Patients who voluntarily agreed and signed the written informed consent form before participating in this study
  • Adult aged 19 years or older
  • American Society of Anesthesiologists physical class (ASA) 1-3
  • Patients scheduled for elective hepatectomy under general anesthesia
  • Patients who require arterial pressure monitoring and additional peripheral venous access for routine anesthesia preparation
  • Non-smokers with normal pulmonary function

排除标准

  • Patients with abnormal findings on electrocardiogram before surgery
  • Patients who cannot undergo peripheral venous puncture

结局指标

主要结局

Pulse pressure variation

时间窗: intraoperative period

from arterial waveform

研究点 (1)

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